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Wednesday's Christmas Eve drawing ended the lottery game's three-month stretch without a top-prize winner. Final ticket sales pushed the jackpot higher, making it the second-largest in U.S. history.

Republican presidential candidate Ted Cruz is barnstorming across Iowa, where his appeal to evangelical voters is making him a threat to GOP front-runner Donald Trump in the first caucus state.

As biotech investments and medical device development falters, hospitals are turning to other avenues to help cut costs: streamlining billing systems and investing in simpler medical products.

Maria Ressa of the Philippines is one of two journalists to have received the Nobel Peace Prize this week, highlighting a message about the need for press freedom.

America's two largest supermarket chains have struck a $25 billion deal to combine. Now the FTC is about to decide whether it will block or allow it, and under what conditions.

The advisory committee makes recommendations to the Centers for Disease Control and Prevention on the nation's vaccine schedule. Any changes could affect vaccinations for millions of children.

Tuesday on Lake Effect:The Precious Lives series features a conversation on the impact of gun violence with Milwaukee alderman Ashanti Hamilton and state…

Wednesday on Lake Effect:The 6th annual VA Mental Health Summit takes place at the UWM Student Union this Saturday. We learn why the Zablocki VA Medical…

Because of a Halloween boost, "Thriller" helps Jackson hit some major chart milestones.

The IRS gave some conservative groups extra, improper scrutiny. Now there's a bipartisan request for the IRS to answer dozens of questions. Read the queries and demands for information from the top Democrat and top Republican on the Senate Finance Committee.